Whole genome amplification using a degenerate oligonucleotide primer allows hundreds of genotypes to be performed on les...
Published in Proceedings of the National Academy of Sciences
Genetic analysis of limiting quantities of genomic DNA play an important role in DNA forensics, paleoarcheology, genetic disease diagnosis, genetic linkage analysis, and genetic diversity studies. We have tested the ability of degenerate oligonucleotide primed polymerase chain reaction (DOP-PCR) to amplify picogram quantities of human genomic DNA f...
