Genome-wide Linkage Analyses of Quantitative and Categorical Autism Subphenotypes
Published in Biological Psychiatry
Background The search for susceptibility genes in autism and autism spectrum disorders (ASD) has been hindered by the possible small effects of individual genes and by genetic (locus) heterogeneity. To overcome these obstacles, one method is to use autism-related subphenotypes instead of the categorical diagnosis of autism since they may be more di...
