Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia.
...Published in Science (New York, N.Y.)
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain elusive. We hypothesize that individually rare structural variants contribute to the illness. Microdeletions and microduplications >100 kilobases were identified by microarray comparative genomic hybridization of genomic DNA from 150 individuals with schizoph...
